Nestled in the Arroios district of Lisbon, Guesthouse Pena Lisbon is approximately 20 minutes' walk from The National Museum of Contemporary Art. The guest house also includes a car park.

Miradouro do Torel Park is merely 450 metres away, while Rossio train station is in the vicinity of the hotel. The adjacent Church of Sao Vicente of Fora is just 1.7 km from the Guesthouse Pena Lisbon, and Humberto Delgado airport is 5 km away. The moorish Castle of Sao Jorge is nearly 25 minutes' walk away, and Intendente underground station is a stone's throw from the property. Campo dos Martires da Patria bus stop is located a mere 250 metres from this Lisbon hotel.

Guests may find the restaurant Cervejaria Ramiro steps away from the accommodation.