Featuring a seasonal outdoor swimming pool, the 5-star Grand House - Relais & Chateaux Vila Real de Santo Antonio hotel is around a 25-minute walk from Plaza de La Coronacion. Located a short way from Centro Cultural Antonio Aleixo Museum, the hotel overlooks the city and invites guests to have a drink at a lounge bar.

The centre of Vila Real de Santo Antonio can be reached in 5 minutes' walk of this smoke-free hotel, and such cultural venues as Casa do SAL Local History Museum are 3.6 km away. Foz do Guadiana is approximately 10 minutes away by car, while Estatua Do Marques de Pombal is merely 250 metres from the Grand House. The property lies within 30 minutes' walk of Guadiana River Transport. Vila Real de Santo Antonio bus station is also within easy reach of this Vila Real de Santo Antonio hotel.

Grand House - Relais & Chateaux hotel has 30 rooms with a dressing area and a sitting area. A flat-screen TV with satellite channels along with a mini-bar are provided. Bedrooms come with couch beds. Bathrooms are equipped with a walk-in shower and a separate toilet, as well as comforts such as a hair dryer and dressing gowns.

Quiosque Carioca is located about 6 km from the Grand House Vila Real de Santo Antonio and serves Portuguese food.